Today is December 1st. Have your paper and pencil ready to write down important information. A lot of attention has been directed to Marc Correas protocol published in the current edition of Positive Health News, Report No 15. Earlier today, I talked with Marc and asked him how he was doing. He replied I am doing great physically. I have not felt this good in years. He told me his doctor was concerned about his viral load for HIV and took two more tests since September. During the summer, Marcs protocol reduced his viral load from 272,000 down to 560. The last two tests showed first a slight increase to 900, then a drop to the 700 range. Marc said he has not yet answered all the mail he has received due to some family conflicts that have caused him some emotional distress. As one example, he told me his grandparents, whom he is living with, are threatening to divorce each other. Marcs successful results validates his protocol and the concept of rotating antiviral herbs/therapies every 30 days.
Another long term survivor is Jim Prentice whose protocol and phone number are published in the current edition. Last week he told me his latest lab results. His CD8s have increased to 900 from 670. His CD4s decreased from 70 to 63. His WBCs are 8400, up from 5000, and his viral load (PCR) decreased from 40,000 (June, 1997) to 840 (Nov. 1997). He reports he feels like a million, has no opportunistic infections and takes no prophylasis to prevent PCP. Like Marc Correa, he has excellent responses to the weekly DNCB topical applications indicating good DTH and cell mediated immunity.
In regards to the CD4 cells, the quality is more important than the quantity. To prevent opportunistic infections, we need large numbers of CD4s in the lymph nodes, organs and tissues producing TH1 type cytokines. TH1 cytokines stimulates the CD8 cytotoxic lymphocytes to destroy virus infected cells. Because TH1 CD4 cells migrate from the blood to the lymph nodes and tissues, total CD4 counts can be very misleading and often underestimate the total number present in the body. High levels of TH2 type CD4 cells tend to circulate in the blood and stimulate antibody production and are not effective against AIDS-defining opportunistic infections. In CFIDS, very high levels of TH2-type CD4s in the blood are not protecting people from constant outbreaks of thrush and candidiasis. In CFIDS, CD4/CD8 ratios often run from 3.0 to as high as 6, which is way above the norm of 1.8. Like AIDS and cancer, there is a failure of NK function and CD8 cytotoxic lymphocyte activity. Weekly DNCB topical applications would be as beneficial to cancer and CFIDS patients as they are to persons affected by AIDS.
This month, I am adding Turmeric (Curcumin) to the list of antivirals that can be rotated every 30 days. A search I done at the National Library of Medicine on Turmeric turned up a number of abstracts which indicated Turmeric or Curcumin has the following effects: 1. It suppresses several inflammatory prostaglandins and leukotrienes. 2. It reduces Tumor Necrosis Factor (TNF). 3. It is an Integrase inhibitor that reduces HIV replication. 4. It is a protease inhibitor. 5. It shows anticancer activity. 6. It increases HDL, the good cholesterol and decreases LDL, the bad cholesterol. 7. It has significant antioxidant activity. Like Alpha Lipoic acid, Selenium and even the protease inhibitor, Ritonavir (Norvir), Curcumin inhibits the NF KappaB pathway. Inhibiting the NF-KB pathway reduces B cell production of antibodies and increases apoptosis of cancer cells. A file on Curcumin is being compiled and will be available shortly. Suggested dose is 2 capsules 2 or 3 times daily. Curcumin may be rotated every 30 days along with the other antivirals listed in our current newsletter.
Persons are strongly advised NOT TO USE any herbs on a continuous daily basis unless you know their immunological effects. To do so could cause yourself considerable harm. Note: The December, 1997, message posted here was changed and corrected on 2/1/98 deleting references to DDC (HIVID).
Today is Nov. 1st. By now, most of our readers should have received the latest issue of Positive Health News, Report No 15. Bulk mailings of newsletters to over 300 distribution centers should be completed in the next few days.
Now, for updated news. Last week, I received a phone call from the Center for Disease Control (CDC). I was told that Positive Health News was among 23 newsletters selected to be added to AIDSLINE at the National Library of Medicine (NLM). Beginning in January, 1998, thousands of persons affected by AIDS will have direct internet access to articles published in Positive Health News about immune based diagnostics and treatments. A spokesperson at the CDC told me AIDSLINE can now be accessed through the internet at www.healthgate.com/HealthGate/MEDLINE. I was also told a wealth of information was available at www.critpath.org. The CDC is to be commended for its decision to allow a diversity of views to be made available through AIDSLINE.
In the latest issue of Positive Health News, I have published An Open Letter to Dr. Anthony Fauci of the NIAID requesting that the NIAID and the NIH set aside funds to develop a low cost model treatment protocol for persons with AIDS using immune based treatments and diagnostics as well as low cost over-the-counter herbal and lipid antivirals such as lauric acid. We have also asked for lymph node biopsies of 100 AIDS patients to determine if the variant A strain of HHV-6 is an essential partner with HIV in AIDS progression or just another opportunistic infection. If a study by the NIAID and the NIH determines that HHV-6A is an essential partner with HIV in the development of immune dysfunction in AIDS, it would alter the disease model and lead to more effective diagnostics and treatments.
Our readers who receive the current newsletter are asked to make 3 photocopies of the letter to Dr. Fauci, sign each letter and mail one to Dr. Fauci and one to your Congressman and to both your US Senators. Include a handwritten note to your elected representatives asking them to sponsor legislation to provide government funding under Medicaid and ADAP for up to $500 a month to pay for immune based diagnostics and treatments including nutritional and dietary supplements. The most common complaint I hear is from persons on disability who want to use immune based and nutritional therapies but have no funds to do so. If the government can spend up to $30,000 a year on expensive pharmaceutical drugs for each person with AIDS, they should be able to provide $6000 a year for nutritional and immune based treatments that do not have a long list of toxic side effects, in fact, very few side effects at all have been reported. In order to have a reasonable chance of success at this efforts, strong grassroots support from local communities across the nation will be needed to first get the governments attention. You can help this effort succeed by participating in the letter writing campaign to Congress and to Dr. Fauci.
In the current newsletter, I have a lengthy article on NK911 as an immune modulator to activate Natural Killer Cell function. In order to independently evaluate the effectiveness of NK911, I am asking everyone who uses the product to obtain a Natural Killer Cell Function test before starting on NK911 and 4 to 6 weeks later to determine how much improvement has occurred in the NK function and to report your results back to me.
Another product that I mentioned but did not write about sufficiently is Bio Pro Thymic Protein A. This is a sublingual type of Thymic extract that contains a growth factor called Protein A which is not well absorbed in the gastrointestinal tract. Two persons have had very good results increasing white blood cell counts and total lymphocyte counts with this product. Only one packet a day is recommended. Bob, a reader from Florida, volunteered to have his name and phone number published in the current newsletter increased his WBCs to 9300 and his lymphocyte percent to 41% using Bio Pro Thymic Protein A. Unfortunately, I incorrectly listed his area code as 602 in the newsletter and persons calling are finding the number disconnected. His correct phone number is 305-595-9237. Since the white blood cells are the foundation of your immune system and they include all the T cells, NK cells and macrophages, anyone whose total WBC count has dropped below 5000 should consider using Bio Pro Thymic Protein A. Once the total WBCs are over 6000, you can reduce the dosage to one packet 3 times a week to maintain them at this higher level. Note: Positive Health News, Report No 15, should be on our internet web site by Nov 7th. Return to home page to access the newsletter.
Today is October 1st. It will be about one more week before the next edition of Positive Health News will be in the printers. A revised 6th edition of How To Reverse Immune Dysfunction was completed two weeks ago. It was updated through PHN NO 14. Now for updated news.
I spoke with Marc Correa earlier today who is only using immune based and nutritional therapies. He reports his latest lab results. His CD8 count is up to 1080, CD4s up to 274, WBCs up to 6000 and PCR count is down to 560. His complete protocol, which closely follows the recommendations in the last newsletter, will be published in the next newsletter. He reports he feels like a million dollars and has not had one opportunistic infection in the past 4 months. The true value of immune based therapies cannot be measured, initially, in terms of CD4 counts or even HIV viral load. Many physicians do not understand the value of immune based diagnostics and refuse to order these tests. The most important diagnostic tests in AIDS are those that tell you if you have natural immunity against opportunistic infections. After all, what is the value of non-detectable HIV viral loads and higher CD4s counts if you break out with infections like Retinitis, MAC, PML, Toxoplasmosis, PCP, Cryptococcus, Candida, KS, Lymphomas, cancer or leukemia? HIV infection will not kill you, opportunistic infections will. The three most important immune based diagnostic tests that will indicate if you have natural immunity against opportunistic infections are the following. 1. Natural Killer Cell Function. 2. Multitest CMI and 3. B and T cell function.
Natural Killer cell function is measured in lytic units. The average NK lytic unit count in a normal healthy person is 135. A lytic unit is measured in a lab when NK cells are placed in contact with cancer cells. If the NK cells do not kill any cancer cells, your Natural Killer cell function is zero. If 100 cancer cells are lysed or destroyed, your NK function is 100 lytic units. Functional Natural Killer cells can provide you with natural immunity against cancer, viral and bacterial infections and all the opportunistic infections involved in AIDS. NK cells operate independently of the CD4 cells. Unlike the B cells, Dentritic, monocytes and macrophages, the NK cells do not need to hold a conference with the CD4 Helper cells to be functional. Functional Natural Killer cells are like a policeman, judge, jury and executioner all in one. Anyone with a NK function of less than 25 lytic units is severely immune compromised. In September, one person with CFIDS and 4 persons with AIDS told me their latest NK function test results. The person with CFIDS had 3 lytic units and has to drink 1/2 cup of olive leaf tea twice a day or she feels like something is eating her brain (possibly HHV-6). The 4 persons with AIDS reported the following results: One had 3 lytic units along with Retinitis and a MAC infection. One had 4 lytic units with PML and a MAC infection. One had 24 lytic units and the 4th had 26. The two AIDS cases with a NK function of 24 and 26 did not have any active infections at this time. A goal for anyone with AIDS or CFIDS is to increase their NK lytic units up to 50 as quickly as possible and eventually to increase them to 100 or higher.
The second test is Multitest CMI which demonstrates Delayed Cutaneous Hypersensitivity and Antigen Presentation. This occurs when the immune system is challenged with antigens in a skin test. Without antigen presentation, no immune response can occur to any infection.
The third test measures the lymphocyte proliferative response of B cells, CD4 and CD8 cells under mitogen stimulation. This test measures the ability of the immune system to clone an army of specific subsets of white blood cells to attack the invading pathogen. If all three test show normal values, you no longer have either AIDS or CFIDS and any symptoms you may have had will be gone. A failure of Natural Killer cell function and cell mediated immunity now links 4 major epidemics. They are AIDS, CFIDS, Candidiasis and Cancer. T and B Cell Function tests and Natural Killer Cell Function tests are available through Immunosciences Labs in Beverly Hills, CA. Phone No 800-950-4686 or 310-657-1077. A catalog of available lab tests is provided on request. MultiTest CMI is available though Connaught Labs in Swiftwater, PA 800-822-2463 or 717-839-7187. A Q and A brochure about Multitest is available on request.
Last month, I reported on NK911 that contains a transfer factor called Biotic Code 614. A small controlled study showed that Biotic Code 614 can increase NK function 8 fold in 2 weeks. Last week, a mother whose son has Kaposi Sarcoma told me that after her son used Biotic Code 614 at a high intensity dose for 2 weeks that the KS lesions had stopped growing. A high intesnity dose is to take 3 capsules 3 or 4 times a day for 3 days per week, then skip 4 days and repeat the same dosage level. More information on Biotic Code 614 will be published in my upcoming newsletter. A 30 page report on Biotic Code 614 by Dr. Jesse Stoff MD is now available from Keep Hope Alive and includes suggested protocols for using NK911. Include $3.00 to cover printing and postage costs. NK911 is available through PH Products - 414-242-5650 or Novus Research at 602-497-5353 or Mike Davis at 650-654-1795. Thank you for calling. This message will be updated again on November 1st.
Today is Sept 1st. Have your paper and pencil ready to write down important information. Within a few days, a new edition of How To Reverse Immune Dysfunction is expected to be completed. It will be updated through Positive Health News, Report No. 14. By the end of this week, I will be starting on my next newsletter, Report No 15 which should be finished by the end of September.
Last month I reported on Marc Correas results using immune based therapies along with coconut oil and the herbal antivirals which are rotated every 30 days. He reported in August his viral load dropped to 971 and his CD8s increased to 1080. However, more important than these numbers are that he feels great and has not had a single opportunistic infection all summer. Two local PWAs, Jim and Doug who are also using immune based therapies along with coconut oil and Larreastat have reported viral load counts of 800 and 2400 respectively. Both all report feeling great and have not had a single O.I. since starting on these protocols. None of the three persons I mentioned here are using drug cocktails and none are using any drugs to prevent PCP or any other opportunistic infection. A copy of Marc Correas protocol is available by send a SASE to Keep Hope Alive. On August 23rd, Jim Prentice and I met with Mary Enig PH.D. in Milwaukee. Enig told us that Lauric acid in coconut oil is hydrolyzed in the small intestines into Monolaurin, a substance that dissolves the lipid envelope of lipid envelope viruses like HIV, HHV-6, CMV, EBV and others.
Last month , I reported on a new product that activates Natural Killer Cell function called NK911. NK911 contains Biotic Code 614, developed by Dr. Stanley Olsztyn. Last month, I received a report on Biotic Code 614 written by Dr. Jesse Stoff MD of Tucson, AZ. Dr. Stoff wrote a report on 46 patients using Biotic Code 614 and the effect the product had on Natural Killer(NK) Cell function. In every single case, NK function significantly improved, usually doubling in the first 2 weeks with increases by 20 fold or more over a period of several months. He has tested the product in patients with cancer, CFIDS and AIDS. In one CFIDS case, as the NK function improved, the HHV-6 titers dropped to non-detectable levels. In one AIDS case, the NK function was 1 lytic unit in Dec. 1994 and the HIV viral load was 559,762. One year later, his NK lytic units were up to 68 and his viral load count was down to 919. Besides improving Natural Killer Cell function, transfer factor also improves antigen presentation and Delayed-Type Hypersensitivity(DTH) or Delayed Cutaneous Hypersensitivity(DCH), both of which measure cell mediated immune responses. MultiTest C.M.I skin test reactions to antigens should improve with transfer factor as well as improved DTH reactions to DNCB topical applications. The implications of these improvements in immune function are fewer opportunistic infections or shorter durations for existing ones.
Three persons using NK911 last month reported to me the following results. Rich Carson of the CFIDS Buyers Club said it wiped out a sinus infection in 3 days. Another person who had chronic low body temperature reported immune activation in the form of low grade fevers and a third person with wasting reported better appetite and a 4 lb weight gain in two weeks. The usual dose is one capsule 3 times a day for 3 days and then skip the next 4 days and repeat the same schedule the following week. NK911 is available through PH Products - 414-242-5650 or Novus Research at 602-497-5353 or Mike Davis at 650-654-1795. A 30 page information packet on Biotic Code 614 is available for $3.00 from Keep Hope Alive and include the complete report by Dr. Jesse Stoff and an expanded distributor list. Based on the information I have reviewed, NK911 may be used as an alternative to Naltrexone or may be used along with Naltrexone to further activate Natural Killer cell function. Thank you for calling. This message will be updated on October 1st. Keep Hope Alive, PO Box 270041, West Allis, WI 53227.
Today is August 1st. Within the past month, one of our readers who has been HIV+ for 12 years was pressured by his physician to start a drug cocktail combination with protease inhibitors. Within 7 days after starting on the combination, he developed Retinitis. The development of serious opportunistic infections in persons using protease inhibitors is evidence of a failure of cell-mediated immunity. I referred the reader to the BHT treatment for Retinitis used by Marc Correa and reported in last months message. Meanwhile, published reports linking the use of protease inhibitors to the rapid onset of Retinitis are now appearing in medical journals. These reports are accessible through AIDSLINE at the National Library of Medicine.
In June, the FDA sent a letter to physicians treating AIDS patients alerting them that as many as 1 in 100 persons using protease inhibitors are developing elevated blood sugar levels and some could go on to develop diabetes. Meanwhile the CDC reported in July that the death rate from AIDS dropped 19% in the first 9 months of 1996 as compared to the first 9 months of 1995. In the first nine months since protease inhibitors became widely available in January, 1996, the CDC reported 30,700 deaths from AIDS. A more disturbing question remains: why is it taking so long for the data for the last 3 months of 1996 and the first six months of 1997 to become available? Based on limited data I have analyzed, I am estimating that 600 to 700 persons continue to die from AIDS every week in the United States. The promises of Vancouver that protease inhibitors, by reducing HIV viral loads to non-detectable levels, would stop the death and dying is proving to be a big lie, but a profitable one at that, paid for mainly by US taxpayers.
Now for better news. Marc Correa, who developed 5 major opportunistic infections (OIs) after he went on the drug cocktail combinations, got rid of all of them after he stopped the drug cocktails and went on an aggressive program of immune based and nutritional therapies. The OIs he developed were Kaposi Sarcoma, Retinitis, PCP, disseminated herpes, and thrush. At the time all five OIs disappeared, his lab numbers looked at their worse. His CD4 count dropped to 4 and his HIV viral load increased from non-detectable levels to 272,000. However, his labs numbers have since improved. On July 5th, he reported his HIV viral load dropped to 33,000, his CD4 count increased to 210 and his CD8s are up to 976. He remains symptom free. It is important to remember that the disappearance of the 5 opportunistic infections preceded improvements in his lab numbers. Marc has written out his complete protocol. I will send a copy to anyone on request. Write to me and include a SASE.
In another local case, D.W. of Racine WI, had been on Crixivan, AZT and 3TC for over one year while his weight and health deteriorated. This happened in spite of increases in his CD4 counts and a very low HIV viral load of 2400. In Dec., 1996, he began to add nutritional and immune based therapies including Naltrexone, Beta 1, 3 Glucan, Complete Thymic Formula and Designer Protein. He also used one bottle of Transfer Factor and has been using Larreastat for several months. Six weeks ago, he added coconut oil - 3 tblsp daily to his protocol along with evening primrose oil and Jarrowdophilus. Late in June, he quit the Crixivan, AZT and 3TC. Three weeks later he had lab work done. Surprise, no increase in his HIV viral load. It remained at the same 2400 level it was 3 months ago and he had increases in both his CD4 and CD8 counts. He feels so good he left on vacation this week.
Other news. Knox and Carrigan have introduced a new blood test for HHV-6, variants A and B, called Rapid Culture Assay. The blood test for HHV-6 is now available as an alternative to the lymph node biopsy. Recently, Konstance Knox told me that Donald Carrigan and herself had found the variant A strain of HHV-6 in every single AIDS patient for which they used lymph node biopsies. Also, a search I done on AIDSLINE at the NLM last week turned up 220 published articles on the role of HHV-6 in AIDS. This is up from 195 articles which I found in February , 1997.
A new product came to my attention last month which activates Natural Killer Cell function. It is called Biotic Code 614 and is sold under the name NK911. Biotic Code 614 contains a patented transfer factor that studies have indicated can double NK function in just 2 weeks. Dr. Jesse Stoff MD has used Biotic Code 614 in his clinical practice for the past 3 years and has written a report of the results in 46 patients having conditions ranging from AIDS to CFIDS to Candidiasis to Cancer. Natural Killer cell function was measured in all 46 patients and improved in every one of them along with very significant improvements in their health. Some patients had up to a 20 fold increase in NK function. A copy of his lengthy report is available (1) A $5.00 donation to cover costs is suggested. This product does not require a prescription. I am considering suggesting NK911 as an alternative to Naltrexone or it may be used with Naltrexone to help restore NK function more rapidly. Thank you for calling. This message will be updated on Sept. 1st. Mark Konlee
1. Keep Hope Alive, PO Box 270041, West Allis, WI 53227 Phone No. 414-548-4344
Today is July 1st. Within the past 2 and 1/2 weeks, 16,000 of 20,000 copies of Positive Health News, Report No 14, have been mailed out. Many of the bulk mailings are still enroute to our distributors and should arrive within the next week. This months message supplements 28 pages of information appearing in the 32 page newsletter. Now for updated news.
Mark Correa, a PWA from California who developed Retinitis after starting on a protease inhibitor drug cocktail combination told me he cleared the infection from his left eye in 7 days by adding 1000 mg of BHT (Butylated Hydroxytoluene) to the lemon/olive oil drink. He took this twice daily. He used a total of 2000 mg of BHT daily. After 7 days, he reported the cloudiness in his eye cleared up. He then reduced the dose of BHT to 1000 mg daily. He has also received an injection of Cytovene every two weeks but his doctor told him he has never seen a case of Retinitis clear up this fast. In his latest examination, the doctor found no traces of Retinitis remaining and then questioned whether the first diagnosis was an error. Correa was interviewed in the latest issue of Positive Health News. He has discontinued drug cocktail combinations and is now using immune-based and nutritional therapies and told me recently he has never felt so good.
In the April/May, 1997 issue of Alive and Kicking (We The People, Phila, PA), an article titled New Infections linked to Protease Inhibitor Use reported that physicians in several cities both here and abroad are finding an increase in Retinitis occurring in many patients after starting the use of protease inhibitor/nucleoside drug combinations. The article reported that one person developed CMV Retinitis only 9 days after starting on ritonavir. Meanwhile, the US Food and Drug Administration has, within the past 3 weeks, sent a letter to physicians treating AIDS patients advising them to monitor blood sugar levels. The FDA reported that as many as 1 in 100 people may develop elevated blood sugar levels or diabetes as a result of using protease inhibitors.
In the latest newsletter, I reported on 5 cases where persons used Lauric acid from coconuts, coconut milk or oil to inactivate HIV, HHV-6 - variant A, and other lipid envelope viruses. Since publication of the newsletter, two persons with AIDS have called and reported HIV viral load drops as a result of drinking canned coconut milk. One person who consumed 1/2 can (about 7 ounces) daily reported a 50% drop in HIV viral load in 4 weeks. Another person with an HIV viral load of 60,000 reported it dropped to 800 in 6 weeks. He consumed 1/2 can twice daily or a total of 14 ounces. He also used other immune based therapies including Naltrexone, DNCB, RyVital, Beta 1, 3 Glucan and DHEA. He eliminated trans fatty acids and most forms of sugar from his diet and also took evening primrose oil and vitamins and minerals from super foods and whole food sources. Neither person used any protease inhibitors or nucleosides.
Recently I learned that two major pharmaceutical companies are now pilot testing new drugs for treating Human Herpes Virus 6, variant A (HHV-6-A). The source from whom I learned the names of the drug companies asked me not to disclose their identity at this time. From another source I have learned that top government scientists have been meeting behind closed doors to discuss this virus - HHV-6A. This source indicated that it was not at liberty to disclose what was discussed at these meetings.
Why the secrecy surrounding HHV-6A? For the past 13 years, the public has been told that HIV alone is the cause of AIDS. As I see it, top government scientists are probably waiting until the drug companies come up with an effective treatment for HHV-6A before breaking the news to the world of a second AIDS virus. Another problem is that a simple diagnostic test (urine, blood or saliva) is needed to determine if someone has been exposed to HHV-6A and no one has developed such a test at this time. Right now, only lymph node biopsies can accurately determine if a person is infected with HHV-6A. These tests are now available through Knox and Carrigan as reported in my latest newsletter. Because the government has not had the courage to step up to the microphone and tell the world of the role of HHV-6A in AIDS and CFIDS, the popular press continues to ignore this virus and one of the most important stories of our times remains untold.
Thank you for calling. This message will be updated on August 1st.
Today is June 1st. This months message will be very brief. I am presently finishing up a 32 page newsletter, the largest we ever published, which is expected to go to the printers within the next few days. I expect the newsletter should arrive by June 15th to paid subscribers and to those receiving free subscriptions by June 21st. Positive Health News, Report No 14 should on our internet web site by June 15th. For the next 7 days, persons leaving message can expect a delay in return phone calls. Because the expense of printing and shipping out 20,000 copies has forced us to borrow money for this issue, anyone who can help with a donation, paid subscription or by sending us postage stamps is encouraged to do so. Thank you for calling. This message will be updated on July 1st. Mark Konlee
Today is May 1st. This months subject is immune system resistance to medications (drugs or herbs etc). Many protocol failures may have been erroneously blamed on viral resistance. We have heard many reports from persons with these chronic conditions. Invariably they say that a new protocol (drug or herb) works for a while and then quits working. What causes the medicine or drug to fail?
The answer may be found in impaired liver function and immune system resistance. The liver breaks down hundreds of different chemical substances into metabolites that can be eliminated from the body. If the liver is unable to do its job, these substances circulate in the blood as durable substances. The immune system is programmed to attack and produce antibodies against all foreign antigens, that is, all substances that are not self. This activity goes beyond attacking viruses, fungus and bacteria and includes any foreign protein substance that is durable and unknown to the body - a stranger.
The landscape is scattered with protocols that have failed in the treatment of AIDS, CFIDS, candidiasis and cancer. In the same breath, the very same protocols have produced long term benefits for many people. Why the contrast? Is it because everyone is different? Yes, people react differently, but why? What I am proposing is the differences that exist are in the condition of the patients liver and the degree of activity of the humoral arm of the immune system that produces antibodies against durable substances in the medications. In other words, patient A, who has a sluggish liver and overactive B cells will have rapid protocol failure on any drug or herb that contains durable chemicals. In contrast, patient B, who has a healthy liver and less active B cell production of antibodies will obtain good results from the same protocol for the same condition. It does not matter if you are taking drug cocktail combinations prescribed by your physician or are doing self treatment with olive leaf extract. The window of effectiveness will vary from person to person because of these two variables.
Immune based therapies are favored for these chronic conditions for the long haul as they are non-toxic and there is no development of immune system or viral resistance. However, when the immune system is dysfunctional and the state of the persons health has deteriorated, immune based therapies alone may not work rapidly enough to clear an infection and anti-viral treatment may be needed as an adjunct therapy. A clue on how to use anti-viral therapies more effectively can be found from the success of the Rotation Diet used by persons with multiple food allergies.
RAPID ROTATION MAY RESTORE ANTI-VIRAL EFFICACY WHEN ALL TREATMENTS HAVE FAILED
The concept of the Rotation diet is based on outpacing the immune systems response to certain foods to which a person has developed allergies. For example, if you are allergic to chicken, it has been found that you can still eat chicken if you eat it only once every 5 days. In the 4 intervening days, the foreign proteins and the corresponding antibodies are eliminated. The rotation concept could be appled to any drug or herbal therapy used in treating HIV and HHV-6. In other words, if you have 5 different drugs or herbs that produced positive results for a while and then quit working, they could still be used as an effective anti-viral treatment if a different one were used every day. This rapid rotation would outpace the B cell antibody response directed against the medication. This concept has never before been applied in the treatment of AIDS. If rapid rotation were implemented, it might look like this: Day 1 - Olive leaf extract; Day 2 - DDI; Day 3, Larreastat; Day 4 - Lauric acid (from Coconut milk); Day 5 - St. Johns Wort. Day 6 - start over with the day 1 protocol and repeat the cycle. A more extensive rotation protocol would expand the list of anti-virals to 7 or 10 and these could be rotated on a 7 or 10 day cycle.
MODERATE ROTATION - A 30 DAY CYCLE
Persons just starting a new protocol will not need rapid rotation as no Memory T cells of B cells have developed against the new treatments. In this case, the same anti-virals could be rotated every 30 days and maintain their effectiveness. since the condition of the liver is critical, persons would benefit from using the whole lemon/olive oil drink 3 to 7 times per week. Other herbs beneficial for liver function are parsley, dandelion root and milk thistle. These can be used daily. However, milk thistle should be limited to 200 mg twice daily. In regards to Complete Thymic Formula which contains the herbs echinacea and golden seal, I suggest using it only 3 days per week and using Jarrow Pak Plus for another 3 days and take one day off. In this way, the herbs in both formulas, which are different, will be rotated every 4 days.
Published research indicates that using echinacea intermittently enhances cell mediated immunity while using it daily suppresses it. This is because daily use of this herb causes the CD4 TH1 response to switch to TH2 which turns on B cells antibody activity. The shift of CD4s from TH1 to TH2 may occur with certain drugs like AZT and other herbs. The TH1 response is effective against HIV and HHV-6 as it turns on the CD8 cytotoxic lymphocytes while the TH2 response turns on the antibody response which is not effective against HIV and HHV-6.
In regards to coconuts, Chris D (1) reports 7 straight months of success is keeping his HIV viral load at non-detectable levels while using it as a monotherapy. A second person trying the coconut therapy reported his viral load dropped from 900,000 to 400,000 in 4 weeks. Pure coconut milk is sold in 14 ounce cans in local grocery stores and health food stores. 3/4 of a can daily should be a therapeutic dose. Mix it with equal parts of pineapple juice and divide it in 2 or 3 daily portions.
1. Positive Health News, Report 13
Within the past month, J.P., a local PWA tested the effects of DHEA and SPV-30 on DTH (delayed type hypersensitivity) responses to DNCB topical weekly applications. What J.P. found was that SPV-30 caused a complete loss of DTH responses to DNCB twice. DHEA did not have this effect and actually enhanced the DTH responses. The amount of DHEA used was 50 mg daily. Loss of DTH responses is indicative of a loss of cell mediated immunity. A loss of cell mediated immunity is an immune deficit already apparent in persons with AIDS, CFIDS, candidiasis and cancer. Any drug or herb that suppresses DTH responses or stimulates B cell production of antibodies should not be used on a continuous basis. Antibody production is already in overdrive in these conditions. What is needed is to enhance the immune systems response to intracellular infections. This requires the activation of CD8 cytotoxic lymphocytes (CTLs) and Natural Killer (NK) cells. I am presently working on the next issue of Positive Health News. Persons who want to share their protocols and lab results with us should send them to us as soon as possible.
Transfer Factor is passive immunization
Four major chronic illnesses of our times, AIDS, CFIDS, Candidiasis and Cancer have one major immune deficit in common and that is Anergy or a lack of cell mediated immunity. Cell mediated immunity is the ability of the immune system to eliminate infections inside cells which is in contrast to humoral immunity that uses antibodies to neutralize infections outside of the cells.
Anergy is a condition when the immune system does not respond to a challenge. Multitest CMI, a skin test for Anergy or delayed cutaneous hypersensitivity (DCH), resulting from the use of Antigen-Specific Transfer Factor is looking good. A PWA from new Jersey who had complete Anergy (no skin response) when his immune system was challenged with 7 antigens contained in Multitest CMI reported that after using transfer factor for 10 days, that he had a better than 2mm reaction to 7 of 8 antigens. This means that the transfer factor restored DCH and he no longer has Anergy. What is significant is that transfer factor for 5 of the Multitest antigens, such as Tetanus and Streptococcus, while not contained in the transfer factor, still responded to the Multitest challenge. The wide range of skin reactions to Multitest suggest that the Lanigan product is sensitizing the immune system to react to many more antigens than that for which it was designed. This is good news for persons with Anergy as it indicates they will have a more functional immune system to prevent opportunistic infections.
Last week, A.J. Lanigan told me that he has had over 20 reports of the restoration of Delayed Cutaneous Hypersensitivity (DCH) after the use of his product for 10 days or longer. My own recommendations on using his product is to take one capsule daily for 20 days, then to skip 3 months and to take one daily for 10 days and repeat this cycle again 3 months later. Under this schedule, 40 capsules will last 9 months. The reason you do not need to take transfer factor daily is that once the white blood cells are sensitized, they will retain their memory to attack specific antigens for several months. Taking more transfer factor will not do any harm, nor will it do any good. Persons taking transfer factor for the first time can expect to feel worse before they feel better. In the first few days of using transfer factor, an immune activation will occur which will often result in low grade fevers, flu-like symptoms and sometimes even nausea. These symptoms will resolve in 3 to 10 days. Multitest CMI is an FDA approved test for measuring cell mediated immunity that your physician can provide you through Connaught Labs. Anyone who does not react to Multitest CMI should consider using transfer factor.
Other products that enhance DCH are Beta 1, 3 Glucan and Thymic factors. In regards to Beta 1, 3 Glucan, one capsule twice daily (100 mg ea of beta 1,3 glucan) should be sufficient for most persons. Beta 1, 3 Glucan is derived from the membranes of the common yeast. It activates macrophages and natural killer cells enabling them to eat and digest more foreign antigens from the blood and increases non-specific immunity against all foreign antigens like bacteria, fungus and viruses. Two persons who use DNCB applications weekly have told me that after adding Beta 1, 3 Glucan to their protocol, their Delayed-Type Hypersensitivity (DTH) skin reactions to DNCB increased indicating an improved cell mediated immune response. Others have reported that Thymus capsules and Complete Thymic Formula have increased their DTH responses to DNCB.
ACT-UP San Francisco reports that products that decrease DTH responses include hydrocortisone, prednisone and other steroids. Some persons have also reported a decrease in DTH responses to DNCB after using SPV-30 while others have not noticed any change in the DTH responses. Persons who not getting a skin response to DNCB who are also using steroids or SPV-30 should discontinue these products and add Beta 1, 3 Glucan and Thymic factors to help restore DCH. (This paragraph was revised 4/26/97)
Other factors that suppress cell mediated immunity include pesticides and chemicals found in food, water and in the air. Pectin found in apples and in the rinds of citrus fruits helps remove heavy metals and toxins. The whole lemon/olive oil drink, by removing poisons, heavy metals and toxins from the liver, lymph and blood, will help improve cell mediated immunity. Drinking lots of clean water, fruit and vegetable juices will help tremendously in detoxifying the body.
In regards to herbs, those that are used for colds and flus and stimulate antibody responses should only be used intermittently, not daily. These include golden seal and echinacea. The herbs that will be most beneficial for persons with AIDS, CFIDS and chronic candidiasis are those that have a long history of safe and effective use in the treatment of cancer. Herbs that do not directly kill cancer cells, but stimulate cancer remissions, can only do so by restoring cell mediated immunity - this is - increasing the both the quantity and function of CD8 Cytotoxic lymphocytes and Natural Killer cells. Some of these herbs include Pau DArco or Lapacho, Red Clover and Slippery Elm. I am researching the subject of herbs and will report on it extensively in my next newsletter.
Also, within the past two weeks, I have received an extensive article on the anti-viral properties of Lauric acid, found abundantly in coconut and in coconut oil. According to Mary Enig, Ph.D., Lauric acid dissolves the membranes of all lipid envelope viruses. Both HIV and HHV-6A are lipid envelope viruses. Coconut oil may be substituted for vegetable oil for all cooking and baking needs.
Finally, this month, I am still looking for more volunteers to try Lemon Balm to determine its effectiveness against HHV-6A and HIV. Volunteers may call 414-548-4344 or write to Keep Hope Alive or send a fax to 414-679-2885.
Today is March 1st. By now, most of our readers should have received their copy of Positive Health News, Report No 13. More than 15000 copies have been distributed nationally within the past 3 weeks. If you have not received your copy, fax us a request and include your current address. Fax 414-679-2885.
The main feature article, titled, AIDS PUZZLE SOLVED, reconstructs the current disease model with HumanHerpes Virus 6, variant A, (HHV-6A) replacing HIV as the principle pathogen in AIDS progression. HIV has a lessor role in AIDS as a supporting co-factor that stimulates HHV-6 replication (through the HIV tat gene). A consensus of current scientific research indicates that HHV-6A, not HIV, is an efficient destroyer of cells. The corrected disease model is strongly supported with several excerpts from current and past medical journals.
After publication of Report No 13, I retrieved 195 abstracts from the National Library of Medicine on the role of humanherpes virus 6 in AIDS. Most of this information could not be used in the current newsletter due to lack of space. A matter that concerns me greatly is that, for all the published scientific research on the role of HHV-6A in AIDS, the mass media writers in the arena of AIDS are grossly uninformed and continue to misinform the public on this subject. They are often in too much of a hurry to meet press deadlines to do original investigative reporting.
Incorrect information now being widely disseminated says that AIDS is HIV disease. It is not. Other published reports say that CD4 cells kill the AIDS virus. CD4 cells do not kill any viruses and one article recently said that protease inhibitors were restoring functional immune systems. None of these writers cited even a single scientific publication to support these erroneous statements. If these writers did their homework , they would not be writing and publishing such false and incorrect information. Positive Health News, Report 13, is well documented with excerpts from leading medical journals.
Effective today, Keep Hope Alive will no longer report the results of any protocol based solely on CD4 counts and HIV viral load. I will not be a party to the continued dissemination of numbers that are not definitely relevant to an improved immune status. CD4 counts will only be reported if CD8 counts are also reported and the two will be added together to represent the total T cell count. If the total T cell count (CD4 plus CD8) increase after following a protocol, this will interpreted as a positive improvement in immune status. If the total T cell counts (CD4 + CD8) decrease, this will be interpreted as a decline in immune status.
On the question of evaluating the success of any protocol based on changes in HIV viral load alone, I will not report these results unless the HIV viral load counts are also accompanied with lab results on the beta 2-microglobulin levels. I am not interested in the numbers of plasma HIV viral counts, a virus that does not destroy cells, as a marker that should generate either any excitement or concern unless beta 2-microglobulin levels are also reported. The beta 2 levels do accurately reflect changes in the rate of cell destruction in the body. Since HHV-6A is the only AIDS virus known to destroy cells, decreases in beta 2-microglobulin levels will be used to monitor decreases in HHV-6 activity in the body and decreases in beta 2 levels will be interpreted as a positive development in improved immune status. It is dishonest for anyone to claim that a reduction in HIV viral load correlates to an improved immune status unless they can prove that cell destruction has also declined. There is a very substantial amount of published scientific data that indicates that persons with low beta 2-microglobulin levels are either slow or long term non-AIDS progressors.
Now to address several questions raised in the last newsletter. First, A.J. Lanigan states that antigen specific transfer factor does not contain any virus or pathogen. According to Lanigan, transfer factor (TF) is made in a lab by a local biochemist who brings a purified antigen in contact with human CD4 cells. The CD4 cells produce transfer factor. The antigen-specific transfer factor is then filtered out of the CD4 culture and only pure transfer factor is given to a pregnant cow. The cows immune system is used to multiply the amount of human transfer factor which is later filtered out of the Colostrum. The transfer factor is freeze dried and encapsulated. If kept refrigerated, it should have a shelf life of about 5 years. The dose needed per person will vary from 1 capsule a day to 2 or 3 daily for 10 days or more. Since Multitest CMI has specific antigens for TB and Candida and Lanigans TF is specific for TB and Candida, these two can be used as surrogate markers in evaluating the products effectiveness. If you have Anergy (no skin response) to TB or Candida on Multitest before using TF and good DCH (skin responses) after using TF for 10 days or more, then it is indicative of restored DCH and an improved capability for cell mediated immune responses against these antigens.
In evaluating Lanigan's Beta 1, 3 Glucan, in capsule form, I am interested in having persons compare this product to their earlier results with Oralmat or RyVital and to look for further increases in total T cell counts (both CD4 and CD8s) and to report these results back to us. I still believe that Oralmat or RyVital are effective immune modulators and do not have sufficient information to endorse one product over the other at this time.
On the subject of DHEA, there have been two reports this month that DHEA may suppress cell mediated immunity and increase symptoms in CFIDS patients. Our position on the use of DHEA is being re-evaluated at this time.
Finally, I am looking for volunteers with AIDS or CFIDS to try Lemon Balm (Melissa) herbal tincture as an experimental treatment for HHV-6A and other herpes viruses and to determine if this herb will also inactivate HIV. I will provide free herb samples for persons with swollen lymph nodes, gastro-intestinal distress, neuropathy, sleep disorders and other HHV-6A related symptoms. I have a strong interest in this herb as an anti-viral because of published reports that viral resistance does not develop, its effectiveness (rapid results) and that there are no reports of toxic side effects. Volunteers can write for more information.
Today is February 1st and here is late breaking news.
The winter edition of Positive Health News, Report No 13, has been expanded from its original 16 pages to 28 pages due to ongoing research and new developments. Publication is now 5 weeks behind my original deadline, but it is expected to be in the printers by February 3rd. It should be on our internet web site by February 10th. The publication will contain excerpts from a 3 page letter I received from Martin Delaney, founder and executive director of Project Inform, who responded to comments directed at him in my previous newsletter, Positive Health News, Report No 12.
The newsletter also contains a 16 page article titled AIDS PUZZLE SOLVED, in which I construct what is described as a corrected disease model. In this model I explain why the CD4/CD8 ratio inverts in AIDS and why this is beneficial to the patient and why and how the twin epidemics of AIDS and Chronic Immune Dysfunction Syndrome (CFIDS) are linked by a common virus - Human Herpes Virus 6, of the variant A strain. The article explains the very limited value of the currently emphasized diagnostics that look only at PCR viral load counts for HIV and CD4 counts and ignore the critical importance of the CD8s, Natural Killer cells and the beta 2 microglobulin levels, a test that measures the rate of cell destruction in the body caused by the primary AIDS virus, Human Herpes Virus 6. The correct diagnostics for measuring improvements in immune function are explained in considerable detail including the value of skin tests for Anergy or Delayed Cutaneous Hypersenitivity (DCH); that is Multitest CMI. The article concludes with an expanded list of options for immune based therapies, anti-viral therapies and those that fit both categories. The subject of viral resistance is discussed and explains why strictly anti-viral therapy based on the use of chemicals alone may be doomed to failure. Viral resistance has never been known to develop to immune based therapies.
Two new immune based products are introduced by a small biotech firm in North Carolina owned by A.J. Lanigan. From initial reports, both these products may be able to turn your immune system into a lean, mean fighting machine. They are Antigen-Specific Transfer Factor and a new highly concentrated source of the macrophage activator, Beta 1, 3 Glucan. There is also an article on L-Glutathione and one on inactivating the membranes of lipid envelope viruses. Both HIV and HHV-6 have lipid membranes. More information will need to await to arrival of your newsletter. Finally, while the cost of publishing the 20,000 newsletters is paid, we still need donations or postage stamps in any denomination to help us pay the shipping costs for the bulk of the newsletters which are distributed free. Whoever is in a position to help is encouraged to do so. Thank you for your support and your prayers.
To begin, I wish each and everyone of you a healthy, loving, and Happy New Year. Now, for updated news.
Last month I reported a case of a local PWA who since August, 1996 discontinued standard drug therapy and began drinking 1/2 cup of the home made olive leaf tincture 3 times a day. In 4 months, his CD4 count increased from 8 to 670 and his HIV viral load dropped from 970,000 to 1800. In Dec., this PWA reported his CD4 count is now up to 1020 and his viral load is non-detectable. This PWA refuses to go public with his lab results stating: Ive been through hell. I dont want people examining me publicly with a microscope.
In another case, Jerry from Idaho has been on the home made olive leaf tincture for 4 months using 1/2 cup twice a day. He also drinks 1/4 cup of Colostrum daily which he obtained from a local farmer. He also uses the whole lemon/olive oil drink, Oralmat drops and several home made herbal tinctures. His latest PCR viral load was 250,000. His total white blood cell count is 7,200 and CD8 counts are now over 2000. Jerry reports that all his skin problems are gone along with thrush and fungal problems and that he has no symptoms whatsoever. On December 10th, at my suggestion, he increased his use of the olive leaf tincture to 1/2 cup 3 times a day to see if the higher dosage will bring down viral load. He also plans to order a P24 antigen test which test for a key HIV viral protein. The reason for doing this is that there is a question about the accuracy of the 250,000 PCR figure. If the PCR test result is accurate, there should be high levels of P24 antigen. If the P24 antigen is low or negative, it would indicate that the PCR test result was defective and should be disregarded. Contrary to popular belief, quantitative PCR for HIV does not measure live active HIV viruses, but calculates the number of viruses based on rapid multiplication of a memory gene attach to a chromosome. A problem arises if the virus that creates the memory gene is some virus other than HIV. Under that scenario, the PCR test result for HIV could be completely inaccurate and misleading. Jerry can be reached at 208-234-4291.
In November, I mentioned an over the counter product made from the dessert chaparral, sold under the trade name Larreastat by Novus Research. I have now confirmed that in 3 cases Larreastat has been an effective treatment for Kaposi Sarcoma leading to complete remission of the lesions over a period of 8 to 12 weeks. The dose was 1 capsule twice daily. In the past month, Lenny, a friend of Robert Marra (Brooklyn, NY), had systemic KS lesions on his skin and in his lungs. He used 1/2 cup of olive leaf tea three times a day along with one Larreastat twice daily and 3 Complete Thymus Formula capsules twice daily. One week later, his KS lesions were visibly shrinking. Not to take any chances, his doctor also prescribed DOX-SL. After 3 weeks on this 4 part protocol, his physician reported that 100% of all his KS lesions were gone. Published information I have reviewed says this product may also be useful for genital herpes, CMV, HHV-6, HHV-8, Hepatitis B and HIV. Published research I reviewed indicates that HHV-8 has been found is all biopsies of KS lesions. If anyone tries Larreastat as a monotherapy, I would suggest one capsule every 8 hours or 3 daily. For a combination olive leaf/Larreastat therapy, I would suggest 1/2 cup of home made olive leaf tincture twice daily along with one Larreastat twice daily.
In another development, I have reviewed dozens of published studies on Wakame or Viva Natural, a brown algae (Unaria pinnatifida). Studies have shown it has powerful anti-viral and anti-cancer properties. The use of brown algae needs to be tested in the treatment of AIDS and CFIDS. Research on animals shows that Wakame contains a carotenoid called fucoxanthin that penetrates inside cells. Wakame is sold in some health food stores. Traditionally, it has been used in making Miso soup. The use of Wakame is experimental at this time. You may contact me for more information or wait for the next newsletter.
Publication of Positive Health News, Report No 13, has been delayed for 3 weeks because of new developments and ongoing research. Publication is expected by Jan 21st. In addition, I need to raise about $2000 to cover the cost of printing and mailing out 20,000 copies. Anyone who can help with a donation is encouraged to do so. Otherwise, I may have to reduce the number of bulk copies printed and sent out for free distribution. Thank you for calling. This message will be updated again on Feb. 1st.